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Abundance of BER-related proteins depends on cell proliferation status and the presence of DNA polymerase β

In mammalian cells, murine N-methylpurine DNA glycosylase (MPG) removes bases damaged spontaneously or by chemical agents through the process called base excision repair (BER). In this study, we investigated the influence of POL β deficiency on MPG-initiated BER efficiency and the expression levels...

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Detalles Bibliográficos
Autores principales: Yamamoto, Mizuki, Yamamoto, Ryohei, Takenaka, Shigeo, Matsuyama, Satoshi, Kubo, Kihei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497385/
https://www.ncbi.nlm.nih.gov/pubmed/25829532
http://dx.doi.org/10.1093/jrr/rrv010