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Effects of dose rates on radiation-induced replenishment of intestinal stem cells determined by Lgr5 lineage tracing
An understanding of the dynamics of intestinal Lgr5(+) stem cells is important for elucidating the mechanism of colonic cancer development. We previously established a method for evaluating Lgr5(+) stem cells by tamoxifen-dependent Lgr5-lineage tracing and showed that high-dose-rate radiation stimul...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497386/ https://www.ncbi.nlm.nih.gov/pubmed/25832104 http://dx.doi.org/10.1093/jrr/rrv012 |