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Effects of indirect actions and oxygen on relative biological effectiveness: estimate of DSB induction and conversion induced by gamma rays and helium ions

Clustered DNA damage other than double-strand breaks (DSBs) can be detrimental to cells and can lead to mutagenesis or cell death. In addition to DSBs induced by ionizing radiation, misrepair of non-DSB clustered damage contributes extra DSBs converted from DNA misrepair via pathways for base excisi...

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Detalles Bibliográficos
Autores principales: Tsai, Ju-Ying, Chen, Fang-Hsin, Hsieh, Tsung-Yu, Hsiao, Ya-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497398/
https://www.ncbi.nlm.nih.gov/pubmed/25902742
http://dx.doi.org/10.1093/jrr/rrv025