Chiral Amine Synthesis Using ω-Transaminases: An Amine Donor that Displaces Equilibria and Enables High-Throughput Screening**

The widespread application of ω-transaminases as biocatalysts for chiral amine synthesis has been hampered by fundamental challenges, including unfavorable equilibrium positions and product inhibition. Herein, an efficient process that allows reactions to proceed in high conversion in the absence of...

Descripción completa

Detalles Bibliográficos
Autores principales: Green, Anthony P, Turner, Nicholas J, O'Reilly, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2014
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497610/
https://www.ncbi.nlm.nih.gov/pubmed/25138082
http://dx.doi.org/10.1002/anie.201406571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497610/
https://www.ncbi.nlm.nih.gov/pubmed/25138082
http://dx.doi.org/10.1002/anie.201406571

Ejemplares similares