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How Co-translational Folding of Multi-domain Protein Is Affected by Elongation Schedule: Molecular Simulations

Co-translational folding (CTF) facilitates correct folding in vivo, but its precise mechanism remains elusive. For the CTF of a three-domain protein SufI, it was reported that the translational attenuation is obligatory to acquire the functional state. Here, to gain structural insights on the underl...

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Detalles Bibliográficos
Autores principales: Tanaka, Tomohiro, Hori, Naoto, Takada, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497635/
https://www.ncbi.nlm.nih.gov/pubmed/26158498
http://dx.doi.org/10.1371/journal.pcbi.1004356