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How Co-translational Folding of Multi-domain Protein Is Affected by Elongation Schedule: Molecular Simulations
Co-translational folding (CTF) facilitates correct folding in vivo, but its precise mechanism remains elusive. For the CTF of a three-domain protein SufI, it was reported that the translational attenuation is obligatory to acquire the functional state. Here, to gain structural insights on the underl...
Autores principales: | Tanaka, Tomohiro, Hori, Naoto, Takada, Shoji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497635/ https://www.ncbi.nlm.nih.gov/pubmed/26158498 http://dx.doi.org/10.1371/journal.pcbi.1004356 |
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