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Context-Specific Metabolic Model Extraction Based on Regularized Least Squares Optimization

Genome-scale metabolic models have proven highly valuable in investigating cell physiology. Recent advances include the development of methods to extract context-specific models capable of describing metabolism under more specific scenarios (e.g., cell types). Yet, none of the existing computational...

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Detalles Bibliográficos
Autores principales: Robaina Estévez, Semidán, Nikoloski, Zoran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497637/
https://www.ncbi.nlm.nih.gov/pubmed/26158726
http://dx.doi.org/10.1371/journal.pone.0131875