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Context-Specific Metabolic Model Extraction Based on Regularized Least Squares Optimization
Genome-scale metabolic models have proven highly valuable in investigating cell physiology. Recent advances include the development of methods to extract context-specific models capable of describing metabolism under more specific scenarios (e.g., cell types). Yet, none of the existing computational...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497637/ https://www.ncbi.nlm.nih.gov/pubmed/26158726 http://dx.doi.org/10.1371/journal.pone.0131875 |