Capacity of Broadly Neutralizing Antibodies to Inhibit HIV-1 Cell-Cell Transmission Is Strain- and Epitope-Dependent

An increasing number of broadly neutralizing antibodies (bnAbs) are considered leads for HIV-1 vaccine development and novel therapeutics. Here, we systematically explored the capacity of bnAbs to neutralize HIV-1 prior to and post-CD4 engagement and to block HIV-1 cell-cell transmission. Cell-cell...

Descripción completa

Detalles Bibliográficos
Autores principales: Reh, Lucia, Magnus, Carsten, Schanz, Merle, Weber, Jacqueline, Uhr, Therese, Rusert, Peter, Trkola, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497647/
https://www.ncbi.nlm.nih.gov/pubmed/26158270
http://dx.doi.org/10.1371/journal.ppat.1004966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497647/
https://www.ncbi.nlm.nih.gov/pubmed/26158270
http://dx.doi.org/10.1371/journal.ppat.1004966

Ejemplares similares