Single Turnover Autophosphorylation Cycle of the PKA RIIβ Holoenzyme

To provide tight spatiotemporal signaling control, the cyclic adenosine monophosphate (cAMP)-dependent protein kinase (PKA) holoenzyme typically nucleates a macromolecular complex or a “PKA signalosome.” Using the RIIβ holoenzyme as a prototype, we show how autophosphorylation/dephosphorylation of t...

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Detalles Bibliográficos
Autores principales: Zhang, Ping, Knape, Matthias J., Ahuja, Lalima G., Keshwani, Malik M., King, Charles C., Sastri, Mira, Herberg, Friedrich W., Taylor, Susan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497662/
https://www.ncbi.nlm.nih.gov/pubmed/26158466
http://dx.doi.org/10.1371/journal.pbio.1002192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497662/
https://www.ncbi.nlm.nih.gov/pubmed/26158466
http://dx.doi.org/10.1371/journal.pbio.1002192

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