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Gene-Activated Matrix Comprised of Atelocollagen and Plasmid DNA Encoding BMP4 or Runx2 Promotes Rat Cranial Bone Augmentation

To date, therapeutic method for in vivo gene delivery has not been established on bone engineering though its potential usefulness has been suggested. For clinical applications, an effective condition should be developed to transfer the genes in vivo without any transfection reagents or virus vector...

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Detalles Bibliográficos
Autores principales: Umebayashi, Mayumi, Sumita, Yoshinori, Kawai, Yousuke, Watanabe, Sumiko, Asahina, Izumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497668/
https://www.ncbi.nlm.nih.gov/pubmed/26309793
http://dx.doi.org/10.1089/biores.2014.0057