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Histamine Induces Vascular Hyperpermeability by Increasing Blood Flow and Endothelial Barrier Disruption In Vivo

Histamine is a mediator of allergic inflammation released mainly from mast cells. Although histamine strongly increases vascular permeability, its precise mechanism under in vivo situation remains unknown. We here attempted to reveal how histamine induces vascular hyperpermeability focusing on the k...

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Detalles Bibliográficos
Autores principales: Ashina, Kohei, Tsubosaka, Yoshiki, Nakamura, Tatsuro, Omori, Keisuke, Kobayashi, Koji, Hori, Masatoshi, Ozaki, Hiroshi, Murata, Takahisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497677/
https://www.ncbi.nlm.nih.gov/pubmed/26158531
http://dx.doi.org/10.1371/journal.pone.0132367