Determination of maximum tolerated dose and toxicity of Inauhzin in mice

Reactivating the tumor suppressor p53 offers an attractive strategy for developing cancer therapy. We recently identified Inauhzin (INZ) as a novel non-genotoxic p53-activating compound. To develop INZ into a clinically applicable anticancer drug, we have initiated preclinical toxicity studies. Here...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Qi, Zeng, Shelya X., Lu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497815/
https://www.ncbi.nlm.nih.gov/pubmed/26167454
http://dx.doi.org/10.1016/j.toxrep.2015.02.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497815/
https://www.ncbi.nlm.nih.gov/pubmed/26167454
http://dx.doi.org/10.1016/j.toxrep.2015.02.011

Ejemplares similares