Subcellular Localization of Frizzled Receptors, Mediated by Their Cytoplasmic Tails, Regulates Signaling Pathway Specificity

The Frizzled (Fz; called here Fz1) and Fz2 receptors have distinct signaling specificities activating either the canonical Wnt/β-catenin pathway or Fz/planar cell polarity (PCP) signaling in Drosophila. The regulation of signaling specificity remains largely obscure. We show that Fz1 and Fz2 have di...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Jun, Klein, Thomas J, Mlodzik, Marek
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC449784/
https://www.ncbi.nlm.nih.gov/pubmed/15252441
http://dx.doi.org/10.1371/journal.pbio.0020158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC449784/
https://www.ncbi.nlm.nih.gov/pubmed/15252441
http://dx.doi.org/10.1371/journal.pbio.0020158

Ejemplares similares