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Imaging of reactive oxygen species in focal ischemic mouse brain using a radical trapping tracer [(3)H]hydromethidine

BACKGROUND: Reactive oxygen species (ROS) have been implicated in the pathophysiology of the brain after ischemic stroke. In this study, we investigate the generation of brain ROS after transient focal ischemia in mice using a radical trapping radiotracer, [(3)H]-labeled N-methyl-2,3-diamino-6-pheny...

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Detalles Bibliográficos
Autores principales: Abe, Kohji, Tonomura, Misato, Ito, Miwa, Takai, Nozomi, Imamoto, Natsumi, Rokugawa, Takemi, Momosaki, Sotaro, Fukumoto, Kazumi, Morimoto, Kenji, Inoue, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498001/
https://www.ncbi.nlm.nih.gov/pubmed/26160496
http://dx.doi.org/10.1186/s13550-015-0115-1