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Conformational thermostabilisation of corticotropin releasing factor receptor 1

Recent technical advances have greatly facilitated G-protein coupled receptors crystallography as evidenced by the number of successful x-ray structures that have been reported recently. These technical advances include novel detergents, specialised crystallography techniques as well as protein engi...

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Detalles Bibliográficos
Autores principales: Kean, James, Bortolato, Andrea, Hollenstein, Kaspar, Marshall, Fiona H., Jazayeri, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498186/
https://www.ncbi.nlm.nih.gov/pubmed/26159865
http://dx.doi.org/10.1038/srep11954