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Low alpha-synuclein levels in the blood are associated with insulin resistance

Mutations in the protein alpha-synuclein (SNCA) have been linked to Parkinson’s disease. We recently reported that non-mutated SNCA enhanced glucose uptake through the Gab1-PI3 kinase-Akt pathway and elucidated its effects on glucose regulation. Here, we examined the association of SNCA with insulin...

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Detalles Bibliográficos
Autores principales: Rodriguez-Araujo, Gerardo, Nakagami, Hironori, Takami, Yoichi, Katsuya, Tomohiro, Akasaka, Hiroshi, Saitoh, Shigeyuki, Shimamoto, Kazuaki, Morishita, Ryuichi, Rakugi, Hiromi, Kaneda, Yasufumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498217/
https://www.ncbi.nlm.nih.gov/pubmed/26159928
http://dx.doi.org/10.1038/srep12081