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Leptin administration restores the altered adipose and hepatic expression of aquaglyceroporins improving the non-alcoholic fatty liver of ob/ob mice

Glycerol is an important metabolite for the control of lipid accumulation in white adipose tissue (WAT) and liver. We aimed to investigate whether exogenous administration of leptin improves features of non-alcoholic fatty liver disease (NAFLD) in leptin-deficient ob/ob mice via the regulation of AQ...

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Detalles Bibliográficos
Autores principales: Rodríguez, Amaia, Moreno, Natalia R., Balaguer, Inmaculada, Méndez-Giménez, Leire, Becerril, Sara, Catalán, Victoria, Gómez-Ambrosi, Javier, Portincasa, Piero, Calamita, Giuseppe, Soveral, Graça, Malagón, María M., Frühbeck, Gema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498231/
https://www.ncbi.nlm.nih.gov/pubmed/26159457
http://dx.doi.org/10.1038/srep12067