PPARα and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal

Many acute and chronic anemias, including hemolysis, sepsis, and genetic bone marrow failure diseases such as Diamond-Blackfan Anemia (DBA), are not treatable with erythropoietin (Epo), because the colony-forming unit erythroid progenitors (CFU-Es) that respond to Epo are either too few in number or...

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Detalles Bibliográficos
Autores principales: Lee, Hsiang-Ying, Gao, Xiaofei, Barrasa, M. Inmaculada, Li, Hu, Elmes, Russell R., Peters, Luanne L., Lodish, Harvey F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498266/
https://www.ncbi.nlm.nih.gov/pubmed/25970251
http://dx.doi.org/10.1038/nature14326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498266/
https://www.ncbi.nlm.nih.gov/pubmed/25970251
http://dx.doi.org/10.1038/nature14326

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