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PPARα and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal
Many acute and chronic anemias, including hemolysis, sepsis, and genetic bone marrow failure diseases such as Diamond-Blackfan Anemia (DBA), are not treatable with erythropoietin (Epo), because the colony-forming unit erythroid progenitors (CFU-Es) that respond to Epo are either too few in number or...
Autores principales: | Lee, Hsiang-Ying, Gao, Xiaofei, Barrasa, M. Inmaculada, Li, Hu, Elmes, Russell R., Peters, Luanne L., Lodish, Harvey F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498266/ https://www.ncbi.nlm.nih.gov/pubmed/25970251 http://dx.doi.org/10.1038/nature14326 |
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