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Tumor-Associated Antigen Expressing Listeria monocytogenes Induces Effective Primary and Memory T-Cell Responses Against Hepatic Colorectal Cancer Metastases

PURPOSE: Despite advances in therapy for the treatment of metastatic colorectal cancer, many patients die of hepatic disease. Current immunotherapeutic strategies are likely limited by inhibitory signals from the tumor. To successfully eliminate tumor deposits within an organ, an appropriate immunol...

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Detalles Bibliográficos
Autores principales: Olino, Kelly, Wada, Satoshi, Edil, Barish H., Pan, Xiaoyu, Meckel, Kristen, Weber, Walter, Slansky, Jill, Tamada, Koji, Lauer, Peter, Brockstedt, Dirk, Pardoll, Drew, Schulick, Richard, Yoshimura, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498288/
https://www.ncbi.nlm.nih.gov/pubmed/21979110
http://dx.doi.org/10.1245/s10434-011-2037-0