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Pharmacokinetics of anti-TB drugs in Malawian children: reconsidering the role of ethambutol

BACKGROUND: Current guidelines for dosing of anti-TB drugs in children advocate higher doses for rifampicin and isoniazid despite limited availability of paediatric data on the pharmacokinetics of these drugs, especially from Africa, where the burden of childhood disease remains high. METHODS: Thirt...

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Detalles Bibliográficos
Autores principales: Mlotha, R., Waterhouse, D., Dzinjalamala, F., Ardrey, A., Molyneux, E., Davies, G. R., Ward, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498297/
https://www.ncbi.nlm.nih.gov/pubmed/25759035
http://dx.doi.org/10.1093/jac/dkv039