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Modulation of Group I Ribozyme Activity by Cationic Porphyrins

The effects of cationic porphyrins on the catalytic activities of four group I ribozymes were investigated. A cationic porphyrin possessing four pyridinium moieties (pPyP) inhibited two group IC3 ribozymes (Syn Rz and Azo Rz) and a group IC1 ribozyme (Tet Rz). In the case of a group IA2 ribozyme (Td...

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Detalles Bibliográficos
Autores principales: Matsumura, Shigeyoshi, Ito, Tatsunobu, Tanaka, Takahiro, Furuta, Hiroyuki, Ikawa, Yoshiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498298/
https://www.ncbi.nlm.nih.gov/pubmed/25811638
http://dx.doi.org/10.3390/biology4020251