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Environmental Enrichment Reverses Histone Methylation Changes in the Aged Hippocampus and Restores Age-Related Memory Deficits

A decline in long-term memory (LTM) formation is a common feature of the normal aging process, which corresponds with abnormal expression of memory-related genes in the aged hippocampus. Epigenetic modulation of chromatin structure is required for proper transcriptional control of genes, such as the...

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Detalles Bibliográficos
Autores principales: Morse, Sarah J., Butler, Anderson A., Davis, Robin L., Soller, Ian J., Lubin, Farah D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498301/
https://www.ncbi.nlm.nih.gov/pubmed/25836028
http://dx.doi.org/10.3390/biology4020298