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Simultaneous Pathoproteomic Evaluation of the Dystrophin-Glycoprotein Complex and Secondary Changes in the mdx-4cv Mouse Model of Duchenne Muscular Dystrophy

In skeletal muscle, the dystrophin-glycoprotein complex forms a membrane-associated assembly of relatively low abundance, making its detailed proteomic characterization in normal versus dystrophic tissues technically challenging. To overcome this analytical problem, we have enriched the muscle membr...

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Detalles Bibliográficos
Autores principales: Murphy, Sandra, Henry, Michael, Meleady, Paula, Zweyer, Margit, Mundegar, Rustam R., Swandulla, Dieter, Ohlendieck, Kay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498307/
https://www.ncbi.nlm.nih.gov/pubmed/26067837
http://dx.doi.org/10.3390/biology4020397