Cargando…

Simultaneous Pathoproteomic Evaluation of the Dystrophin-Glycoprotein Complex and Secondary Changes in the mdx-4cv Mouse Model of Duchenne Muscular Dystrophy

In skeletal muscle, the dystrophin-glycoprotein complex forms a membrane-associated assembly of relatively low abundance, making its detailed proteomic characterization in normal versus dystrophic tissues technically challenging. To overcome this analytical problem, we have enriched the muscle membr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Murphy, Sandra, Henry, Michael, Meleady, Paula, Zweyer, Margit, Mundegar, Rustam R., Swandulla, Dieter, Ohlendieck, Kay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498307/ https://www.ncbi.nlm.nih.gov/pubmed/26067837 http://dx.doi.org/10.3390/biology4020397

Ejemplares similares

Proteomic profiling of liver tissue from the mdx-4cv mouse model of Duchenne muscular dystrophy
por: Murphy, Sandra, et al.
Publicado: (2018)

Proteomic identification of elevated saliva kallikrein levels in the mdx-4cv mouse model of Duchenne muscular dystrophy
por: Murphy, Sandra, et al.
Publicado: (2018)

Label-free mass spectrometric analysis reveals complex changes in the brain proteome from the mdx-4cv mouse model of Duchenne muscular dystrophy
por: Murphy, Sandra, et al.
Publicado: (2015)

Proteomic profiling of mdx-4cv serum reveals highly elevated levels of the inflammation-induced plasma marker haptoglobin in muscular dystrophy
por: Murphy, Sandra, et al.
Publicado: (2017)

Concurrent Label-Free Mass Spectrometric Analysis of Dystrophin Isoform Dp427 and the Myofibrosis Marker Collagen in Crude Extracts from mdx-4cv Skeletal Muscles
por: Murphy, Sandra, et al.
Publicado: (2015)

Mass Spectrometric Profiling of Extraocular Muscle and Proteomic Adaptations in the mdx-4cv Model of Duchenne Muscular Dystrophy
por: Gargan, Stephen, et al.
Publicado: (2021)

Subproteomic profiling of sarcolemma from dystrophic mdx-4cv skeletal muscle
por: Murphy, Sandra, et al.
Publicado: (2018)

Dataset on the comparative proteomic profiling of mouse saliva and serum from wild type versus the dystrophic mdx-4cv mouse model of dystrophinopathy
por: Murphy, Sandra, et al.
Publicado: (2018)

Proteome-wide Changes in the mdx-4cv Spleen due to Pathophysiological Cross Talk with Dystrophin-Deficient Skeletal Muscle
por: Dowling, Paul, et al.
Publicado: (2020)

Proteomics reveals drastic increase of extracellular matrix proteins collagen and dermatopontin in the aged mdx diaphragm model of Duchenne muscular dystrophy
por: CARBERRY, STEVEN, et al.
Publicado: (2012)

Dataset on the mass spectrometry-based proteomic profiling of the kidney from wild type and the dystrophic mdx-4cv mouse model of X-linked muscular dystrophy
por: Dowling, Paul, et al.
Publicado: (2020)

Chemical crosslinking analysis of β-dystroglycan in dystrophin-deficient skeletal muscle
por: Murphy, Sandra, et al.
Publicado: (2018)

Extracellular Matrix Proteomics: The mdx-4cv Mouse Diaphragm as a Surrogate for Studying Myofibrosis in Dystrophinopathy
por: Dowling, Paul, et al.
Publicado: (2023)

Comparative gel‐based proteomic analysis of chemically crosslinked complexes in dystrophic skeletal muscle
por: Murphy, Sandra, et al.
Publicado: (2018)

Application of Fluorescence Two-Dimensional Difference In-Gel Electrophoresis as a Proteomic Biomarker Discovery Tool in Muscular Dystrophy Research
por: Carberry, Steven, et al.
Publicado: (2013)

Profiling of Age-Related Changes in the Tibialis Anterior Muscle Proteome of the mdx Mouse Model of Dystrophinopathy
por: Carberry, Steven, et al.
Publicado: (2012)

Mass spectrometric identification of dystrophin, the protein product of the Duchenne muscular dystrophy gene, in distinct muscle surface membranes
por: Murphy, Sandra, et al.
Publicado: (2017)

The Dystrophin Node as Integrator of Cytoskeletal Organization, Lateral Force Transmission, Fiber Stability and Cellular Signaling in Skeletal Muscle
por: Dowling, Paul, et al.
Publicado: (2021)

Altered social behavior and ultrasonic communication in the dystrophin-deficient mdx mouse model of Duchenne muscular dystrophy
por: Miranda, Rubén, et al.
Publicado: (2015)

Protocol for the Bottom-Up Proteomic Analysis of Mouse Spleen
por: Dowling, Paul, et al.
Publicado: (2020)

Proteomic Identification of Markers of Membrane Repair, Regeneration and Fibrosis in the Aged and Dystrophic Diaphragm
por: Gargan, Stephen, et al.
Publicado: (2022)

Mass spectrometry-based proteomic characterization of the middle-aged mouse brain for animal model research of neuromuscular diseases
por: Dowling, Paul, et al.
Publicado: (2023)

100-fold but not 50-fold dystrophin overexpression aggravates electrocardiographic defects in the mdx model of Duchenne muscular dystrophy
por: Yue, Yongping, et al.
Publicado: (2016)

Expression and function of four AAV-based constructs for dystrophin restoration in the mdx mouse model of Duchenne muscular dystrophy
por: Potter, Rachael A., et al.
Publicado: (2023)

The potential of utrophin and dystrophin combination therapies for Duchenne muscular dystrophy
por: Guiraud, Simon, et al.
Publicado: (2019)

Mass spectrometry-based proteomic analysis of middle-aged vs. aged vastus lateralis reveals increased levels of carbonic anhydrase isoform 3 in senescent human skeletal muscle
por: STAUNTON, LISA, et al.
Publicado: (2012)

Characterization of Contractile Proteins from Skeletal Muscle Using Gel-Based Top-Down Proteomics
por: Dowling, Paul, et al.
Publicado: (2019)

Dowling, P.; et al. Characterization of Contractile Proteins from Skeletal Muscle Using Gel-Based Top-Down Proteomics. Proteomes 2019, 7, 25
por: Dowling, Paul, et al.
Publicado: (2019)

Dystrophin Is Required for the Proper Timing in Retinal Histogenesis: A Thorough Investigation on the mdx Mouse Model of Duchenne Muscular Dystrophy
por: Persiconi, Irene, et al.
Publicado: (2020)

Dystrophin Dp71 and the Neuropathophysiology of Duchenne Muscular Dystrophy
por: Naidoo, Michael, et al.
Publicado: (2019)

Therapeutic Strategies for Dystrophin Replacement in Duchenne Muscular Dystrophy
por: Happi Mbakam, Cedric, et al.
Publicado: (2022)

Proteomic profiling of the interface between the stomach wall and the pancreas in dystrophinopathy
por: Dowling, Paul, et al.
Publicado: (2021)

Proteomic profiling of impaired excitation–contraction coupling and abnormal calcium handling in muscular dystrophy
por: Dowling, Paul, et al.
Publicado: (2022)

Proteomic Profiling of the Dystrophin-Deficient mdx Phenocopy of Dystrophinopathy-Associated Cardiomyopathy
por: Holland, Ashling, et al.
Publicado: (2014)

Social stress is lethal in the mdx model of Duchenne muscular dystrophy
por: Razzoli, Maria, et al.
Publicado: (2020)

Cardiac Protection after Systemic Transplant of Dystrophin Expressing Chimeric (DEC) Cells to the mdx Mouse Model of Duchenne Muscular Dystrophy
por: Siemionow, Maria, et al.
Publicado: (2019)

Dual exon skipping in myostatin and dystrophin for Duchenne muscular dystrophy
por: Kemaladewi, Dwi U, et al.
Publicado: (2011)

The discovery of dystrophin, the protein product of the Duchenne muscular dystrophy gene
por: Hoffman, Eric P.
Publicado: (2020)

Increased dystrophin production with golodirsen in patients with Duchenne muscular dystrophy
por: Frank, Diane E., et al.
Publicado: (2020)

Comparative proteomic profiling of soleus, extensor digitorum longus, flexor digitorum brevis and interosseus muscles from the mdx mouse model of Duchenne muscular dystrophy
por: CARBERRY, STEVEN, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_tlgmcm62fqamppd5p31viencuc