A hyperactive piggyBac transposon system is an easy-to-implement method for introducing foreign genes into mouse preimplantation embryos

Transgenic mice are important tools for genetic analysis. A current prominent method for producing transgenic mice involves pronuclear microinjection into 1-cell embryos. However, the total transgenic efficiency obtained using this method is less than 10%. Here, we demonstrate that highly efficient...

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Detalles Bibliográficos
Autores principales: SUZUKI, Shinnosuke, TSUKIYAMA, Tomoyuki, KANEKO, Takehito, IMAI, Hiroshi, MINAMI, Naojiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2015
Materias:
Technology Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498375/
https://www.ncbi.nlm.nih.gov/pubmed/25740401
http://dx.doi.org/10.1262/jrd.2014-157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498375/
https://www.ncbi.nlm.nih.gov/pubmed/25740401
http://dx.doi.org/10.1262/jrd.2014-157

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