Activation-Induced Cytidine Deaminase Initiates Immunoglobulin Gene Conversion and Hypermutation by a Common Intermediate

Depending on the species and the lymphoid organ, activation-induced cytidine deaminase (AID) expression triggers diversification of the rearranged immunoglobulin (Ig) genes by pseudo V (ψV) gene- templated gene conversion or somatic hypermutation. To investigate how AID can alternatively induce reco...

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Detalles Bibliográficos
Autores principales: Arakawa, Hiroshi, Saribasak, Huseyin, Buerstedde, Jean-Marie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC449846/
https://www.ncbi.nlm.nih.gov/pubmed/15252444
http://dx.doi.org/10.1371/journal.pbio.0020179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC449846/
https://www.ncbi.nlm.nih.gov/pubmed/15252444
http://dx.doi.org/10.1371/journal.pbio.0020179

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