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Activation-Induced Cytidine Deaminase Initiates Immunoglobulin Gene Conversion and Hypermutation by a Common Intermediate
Depending on the species and the lymphoid organ, activation-induced cytidine deaminase (AID) expression triggers diversification of the rearranged immunoglobulin (Ig) genes by pseudo V (ψV) gene- templated gene conversion or somatic hypermutation. To investigate how AID can alternatively induce reco...
Autores principales: | Arakawa, Hiroshi, Saribasak, Huseyin, Buerstedde, Jean-Marie |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC449846/ https://www.ncbi.nlm.nih.gov/pubmed/15252444 http://dx.doi.org/10.1371/journal.pbio.0020179 |
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