Cargando…

Delivery of Antibody Mimics into Mammalian Cells via Anthrax Toxin Protective Antigen

Antibody mimics have significant scientific and therapeutic utility for the disruption of protein–protein interactions inside cells; however, their delivery to the cell cytosol remains a major challenge. Here we show that protective antigen (PA), a component of anthrax toxin, efficiently transports...

Descripción completa

Detalles Bibliográficos
Autores principales: Liao, Xiaoli, Rabideau, Amy E, Pentelute, Bradley L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498471/
https://www.ncbi.nlm.nih.gov/pubmed/25250705
http://dx.doi.org/10.1002/cbic.201402290