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Delivery of Antibody Mimics into Mammalian Cells via Anthrax Toxin Protective Antigen
Antibody mimics have significant scientific and therapeutic utility for the disruption of protein–protein interactions inside cells; however, their delivery to the cell cytosol remains a major challenge. Here we show that protective antigen (PA), a component of anthrax toxin, efficiently transports...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498471/ https://www.ncbi.nlm.nih.gov/pubmed/25250705 http://dx.doi.org/10.1002/cbic.201402290 |