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HIV Infection of Naturally Occurring and Genetically Reprogrammed Human Regulatory T-cells

A T-cell subset, defined as CD4(+)CD25(hi) (regulatory T-cells [Treg cells]), was recently shown to suppress T-cell activation. We demonstrate that human Treg cells isolated from healthy donors express the HIV-coreceptor CCR5 and are highly susceptible to HIV infection and replication. Because Treg...

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Detalles Bibliográficos
Autores principales: Oswald-Richter, Kyra, Grill, Stacy M, Shariat, Nikki, Leelawong, Mindy, Sundrud, Mark S, Haas, David W, Unutmaz, Derya
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC449855/
https://www.ncbi.nlm.nih.gov/pubmed/15252446
http://dx.doi.org/10.1371/journal.pbio.0020198