AMPK Signaling Involvement for the Repression of the IL-1β-Induced Group IIA Secretory Phospholipase A2 Expression in VSMCs

Secretory Phospholipase A2 of type IIA (sPLA2 IIA) plays a crucial role in the production of lipid mediators by amplifying the neointimal inflammatory context of the vascular smooth muscle cells (VSMCs), especially during atherogenesis. Phenformin, a biguanide family member, by its anti-inflammatory...

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Detalles Bibliográficos
Autores principales: El Hadri, Khadija, Denoyelle, Chantal, Ravaux, Lucas, Viollet, Benoit, Foretz, Marc, Friguet, Bertrand, Rouis, Mustapha, Raymondjean, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498592/
https://www.ncbi.nlm.nih.gov/pubmed/26162096
http://dx.doi.org/10.1371/journal.pone.0132498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498592/
https://www.ncbi.nlm.nih.gov/pubmed/26162096
http://dx.doi.org/10.1371/journal.pone.0132498

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