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AMPK Signaling Involvement for the Repression of the IL-1β-Induced Group IIA Secretory Phospholipase A2 Expression in VSMCs
Secretory Phospholipase A2 of type IIA (sPLA2 IIA) plays a crucial role in the production of lipid mediators by amplifying the neointimal inflammatory context of the vascular smooth muscle cells (VSMCs), especially during atherogenesis. Phenformin, a biguanide family member, by its anti-inflammatory...
Autores principales: | El Hadri, Khadija, Denoyelle, Chantal, Ravaux, Lucas, Viollet, Benoit, Foretz, Marc, Friguet, Bertrand, Rouis, Mustapha, Raymondjean, Michel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498592/ https://www.ncbi.nlm.nih.gov/pubmed/26162096 http://dx.doi.org/10.1371/journal.pone.0132498 |
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