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Tacrolimus Protects Podocytes from Injury in Lupus Nephritis Partly by Stabilizing the Cytoskeleton and Inhibiting Podocyte Apoptosis

OBJECTIVE: Several studies have reported that tacrolimus (TAC) significantly reduced proteinuria in lupus nephritis (LN) patients and mouse models. However, the mechanism for this effect remains undetermined. This study explored the mechanism of how TAC protects podocytes from injury to identify new...

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Detalles Bibliográficos
Autores principales: Liao, Ruyi, Liu, Qinghua, Zheng, Zhihua, Fan, Jinjin, Peng, Wenxing, Kong, Qingyu, He, Huijuan, Yang, Shicong, Chen, Wenfang, Tang, Xueqing, Yu, Xueqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498640/
https://www.ncbi.nlm.nih.gov/pubmed/26161538
http://dx.doi.org/10.1371/journal.pone.0132724