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Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish

Genetic screens are a powerful tool to discover genes that are important in immune cell development and function. The evolutionarily conserved development of lymphoid cells paired with the genetic tractability of zebrafish make this a powerful model system for this purpose. We used a Tol2-based gene...

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Detalles Bibliográficos
Autores principales: Seiler, Christoph, Gebhart, Nichole, Zhang, Yong, Shinton, Susan A., Li, Yue-sheng, Ross, Nicola L., Liu, Xingjun, Li, Qin, Bilbee, Alison N., Varshney, Gaurav K., LaFave, Matthew C., Burgess, Shawn M., Balciuniene, Jorune, Balciunas, Darius, Hardy, Richard R., Kappes, Dietmar J., Wiest, David L., Rhodes, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498767/
https://www.ncbi.nlm.nih.gov/pubmed/26161877
http://dx.doi.org/10.1371/journal.pone.0131908