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Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish
Genetic screens are a powerful tool to discover genes that are important in immune cell development and function. The evolutionarily conserved development of lymphoid cells paired with the genetic tractability of zebrafish make this a powerful model system for this purpose. We used a Tol2-based gene...
Autores principales: | Seiler, Christoph, Gebhart, Nichole, Zhang, Yong, Shinton, Susan A., Li, Yue-sheng, Ross, Nicola L., Liu, Xingjun, Li, Qin, Bilbee, Alison N., Varshney, Gaurav K., LaFave, Matthew C., Burgess, Shawn M., Balciuniene, Jorune, Balciunas, Darius, Hardy, Richard R., Kappes, Dietmar J., Wiest, David L., Rhodes, Jennifer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498767/ https://www.ncbi.nlm.nih.gov/pubmed/26161877 http://dx.doi.org/10.1371/journal.pone.0131908 |
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