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Quantitative Analysis of MicroRNAs in Vaccinia virus Infection Reveals Diversity in Their Susceptibility to Modification and Suppression

Vaccinia virus (VACV) is a large cytoplasmic DNA virus that causes dramatic alterations to many cellular pathways including microRNA biogenesis. The virus encodes a poly(A) polymerase which was previously shown to add poly(A) tails to the 3’ end of cellular miRNAs, resulting in their degradation by...

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Detalles Bibliográficos
Autores principales: Buck, Amy H., Ivens, Alasdair, Gordon, Katrina, Craig, Nicola, Houzelle, Alexandre, Roche, Alice, Turnbull, Neil, Beard, Philippa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498801/
https://www.ncbi.nlm.nih.gov/pubmed/26161560
http://dx.doi.org/10.1371/journal.pone.0131787