Unique Effects of Acute Aripiprazole Treatment on the Dopamine D2 Receptor Downstream cAMP-PKA and Akt-GSK3β Signalling Pathways in Rats

Aripiprazole is a wide-used antipsychotic drug with therapeutic effects on both positive and negative symptoms of schizophrenia, and reduced side-effects. Although aripiprazole was developed as a dopamine D(2) receptor (D(2)R) partial agonist, all other D(2)R partial agonists that aimed to mimic ari...

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Detalles Bibliográficos
Autores principales: Pan, Bo, Chen, Jiezhong, Lian, Jiamei, Huang, Xu-Feng, Deng, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498891/
https://www.ncbi.nlm.nih.gov/pubmed/26162083
http://dx.doi.org/10.1371/journal.pone.0132722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498891/
https://www.ncbi.nlm.nih.gov/pubmed/26162083
http://dx.doi.org/10.1371/journal.pone.0132722

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