The LMO2 -25 Region Harbours GATA2-Dependent Myeloid Enhancer and RUNX-Dependent T-Lymphoid Repressor Activity

Lim domain only 2 (LMO2) is a transcriptional co-factor required for angiogenesis and the specification of haematopoietic cells during development. LMO2 is widely expressed within haematopoiesis with the exception of T-cells. Failure to downregulate LMO2 during T-cell maturation leads to leukaemia,...

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Detalles Bibliográficos
Autores principales: Bonadies, Nicolas, Göttgens, Berthold, Calero-Nieto, Fernando J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498896/
https://www.ncbi.nlm.nih.gov/pubmed/26161748
http://dx.doi.org/10.1371/journal.pone.0131577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498896/
https://www.ncbi.nlm.nih.gov/pubmed/26161748
http://dx.doi.org/10.1371/journal.pone.0131577

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