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Surviving hypoxia by modulation of mRNA translation rate
Cells can survive hypoxia/anoxia by metabolic rate depression, which involves lowering of mRNA translation rates in an ATP-dependent manner. By activating anaerobic ATP production (glycolysis), the inhibitory influence on mRNA translation in hypoxia can be abolished. In severe hypoxia, glycolysis ca...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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John Wiley & Sons, Ltd
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498934/ https://www.ncbi.nlm.nih.gov/pubmed/19674191 http://dx.doi.org/10.1111/j.1582-4934.2009.00875.x |