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A leaky blood–brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer’s disease brain

This study has used immunohistochemical examination of tissue obtained from Alzheimer’s disease (AD) brains and rat hippocampus injected with Aβ(1-42) peptide to determine effects of induced inflammatory reactivity on integrity of blood–brain barrier (BBB) and viability of neurons. Tissue from AD, b...

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Detalles Bibliográficos
Autores principales: Ryu, Jae K, McLarnon, James G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498946/
https://www.ncbi.nlm.nih.gov/pubmed/18657226
http://dx.doi.org/10.1111/j.1582-4934.2008.00434.x