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Cytosolic renin is targeted to mitochondria and inducesapoptosis in H9c2 rat cardiomyoblasts

One important goal in cardiology is to prevent necrotic cell death in the heart. Necrotic cell death attracts neutrophils and monocytes into the injured myocardium. The consequences are fibrosis, remodelling and cardiac failure. The renin-angiotensin system promotes the development of cardiac failur...

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Detalles Bibliográficos
Autores principales: Wanka, Heike, Keßler, Nicole, Ellmer, Janett, Endlich, Nicole, Peters, Barbara S, Clausmeyer, Susanne, Peters, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498947/
https://www.ncbi.nlm.nih.gov/pubmed/18671756
http://dx.doi.org/10.1111/j.1582-4934.2008.00448.x