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Smart Nanoparticles Based on Hyaluronic Acid for Redox-Responsive and CD44 Receptor-Mediated Targeting of Tumor

BACKGROUND: Since aggressive cancer cells highly express the CD44 receptor compared to normal cells, hyaluronic acid (HA) can be used for CD44 targeting molecule. Since glutathione (GSH) level is normally elevated in the intracellular compartment and in the tumor cell, the fact that disulfide bond c...

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Detalles Bibliográficos
Autores principales: Park, Hyung-Kyu, Lee, Sang Joon, Oh, Jong-Suk, Lee, Sam-Gyu, Jeong, Young-IL, Lee, Hyun Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499038/
https://www.ncbi.nlm.nih.gov/pubmed/26163139
http://dx.doi.org/10.1186/s11671-015-0981-5