Large scale analysis of the mutational landscape in HT-SELEX improves aptamer discovery

High-Throughput (HT) SELEX combines SELEX (Systematic Evolution of Ligands by EXponential Enrichment), a method for aptamer discovery, with massively parallel sequencing technologies. This emerging technology provides data for a global analysis of the selection process and for simultaneous discovery...

Descripción completa

Detalles Bibliográficos
Autores principales: Hoinka, Jan, Berezhnoy, Alexey, Dao, Phuong, Sauna, Zuben E., Gilboa, Eli, Przytycka, Teresa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499121/
https://www.ncbi.nlm.nih.gov/pubmed/25870409
http://dx.doi.org/10.1093/nar/gkv308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499121/
https://www.ncbi.nlm.nih.gov/pubmed/25870409
http://dx.doi.org/10.1093/nar/gkv308

Ejemplares similares