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De novo design of heat-repressible RNA thermosensors in E. coli

RNA-based temperature sensing is common in bacteria that live in fluctuating environments. Most naturally-occurring RNA thermosensors are heat-inducible, have long sequences, and function by sequestering the ribosome binding site in a hairpin structure at lower temperatures. Here, we demonstrate the...

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Detalles Bibliográficos
Autores principales: Hoynes-O'Connor, Allison, Hinman, Kristina, Kirchner, Lukas, Moon, Tae Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499127/
https://www.ncbi.nlm.nih.gov/pubmed/25979263
http://dx.doi.org/10.1093/nar/gkv499