Cargando…

Mutations in the CRE pocket of bacterial RNA polymerase affect multiple steps of transcription

During transcription, the catalytic core of RNA polymerase (RNAP) must interact with the DNA template with low-sequence specificity to ensure efficient enzyme translocation and RNA extension. Unexpectedly, recent structural studies of bacterial promoter complexes revealed specific interactions betwe...

Descripción completa

Detalles Bibliográficos
Autores principales: Petushkov, Ivan, Pupov, Danil, Bass, Irina, Kulbachinskiy, Andrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499132/
https://www.ncbi.nlm.nih.gov/pubmed/25990734
http://dx.doi.org/10.1093/nar/gkv504