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Mutations in the CRE pocket of bacterial RNA polymerase affect multiple steps of transcription
During transcription, the catalytic core of RNA polymerase (RNAP) must interact with the DNA template with low-sequence specificity to ensure efficient enzyme translocation and RNA extension. Unexpectedly, recent structural studies of bacterial promoter complexes revealed specific interactions betwe...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499132/ https://www.ncbi.nlm.nih.gov/pubmed/25990734 http://dx.doi.org/10.1093/nar/gkv504 |