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ATP-dependent motor activity of the transcription termination factor Rho from Mycobacterium tuberculosis

The bacterial transcription termination factor Rho—a ring-shaped molecular motor displaying directional, ATP-dependent RNA helicase/translocase activity—is an interesting therapeutic target. Recently, Rho from Mycobacterium tuberculosis ((Mtb)Rho) has been proposed to operate by a mechanism uncouple...

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Detalles Bibliográficos
Autores principales: D'Heygère, François, Schwartz, Annie, Coste, Franck, Castaing, Bertrand, Boudvillain, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499133/
https://www.ncbi.nlm.nih.gov/pubmed/25999346
http://dx.doi.org/10.1093/nar/gkv505