Cdt1-binding protein GRWD1 is a novel histone-binding protein that facilitates MCM loading through its influence on chromatin architecture

Efficient pre-replication complex (pre-RC) formation on chromatin templates is crucial for the maintenance of genome integrity. However, the regulation of chromatin dynamics during this process has remained elusive. We found that a conserved protein, GRWD1 (glutamate-rich WD40 repeat containing 1),...

Descripción completa

Detalles Bibliográficos
Autores principales: Sugimoto, Nozomi, Maehara, Kazumitsu, Yoshida, Kazumasa, Yasukouchi, Shuhei, Osano, Satoko, Watanabe, Shinya, Aizawa, Masahiro, Yugawa, Takashi, Kiyono, Tohru, Kurumizaka, Hitoshi, Ohkawa, Yasuyuki, Fujita, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499137/
https://www.ncbi.nlm.nih.gov/pubmed/25990725
http://dx.doi.org/10.1093/nar/gkv509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499137/
https://www.ncbi.nlm.nih.gov/pubmed/25990725
http://dx.doi.org/10.1093/nar/gkv509

Ejemplares similares