Small RNA-mediated DNA (cytosine-5) methyltransferase 1 inhibition leads to aberrant DNA methylation

Mammalian cells contain copious amounts of RNA including both coding and noncoding RNA (ncRNA). Generally the ncRNAs function to regulate gene expression at the transcriptional and post-transcriptional level. Among ncRNA, the long ncRNA and small ncRNA can affect histone modification, DNA methylatio...

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Detalles Bibliográficos
Autores principales: Zhang, Guoqiang, Estève, Pierre-Olivier, Chin, Hang Gyeong, Terragni, Jolyon, Dai, Nan, Corrêa, Ivan R., Pradhan, Sriharsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499142/
https://www.ncbi.nlm.nih.gov/pubmed/25990724
http://dx.doi.org/10.1093/nar/gkv518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499142/
https://www.ncbi.nlm.nih.gov/pubmed/25990724
http://dx.doi.org/10.1093/nar/gkv518

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