SLX4 contributes to telomere preservation and regulated processing of telomeric joint molecule intermediates

SLX4 assembles a toolkit of endonucleases SLX1, MUS81 and XPF, which is recruited to telomeres via direct interaction of SLX4 with TRF2. Telomeres present an inherent obstacle for DNA replication and repair due to their high propensity to form branched DNA intermediates. Here we provide novel insigh...

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Detalles Bibliográficos
Autores principales: Sarkar, Jaya, Wan, Bingbing, Yin, Jinhu, Vallabhaneni, Haritha, Horvath, Kent, Kulikowicz, Tomasz, Bohr, Vilhelm A., Zhang, Yanbin, Lei, Ming, Liu, Yie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499145/
https://www.ncbi.nlm.nih.gov/pubmed/25990736
http://dx.doi.org/10.1093/nar/gkv522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499145/
https://www.ncbi.nlm.nih.gov/pubmed/25990736
http://dx.doi.org/10.1093/nar/gkv522

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