Cargando…

Gene target specificity of the Super Elongation Complex (SEC) family: how HIV-1 Tat employs selected SEC members to activate viral transcription

The AF4/FMR2 proteins AFF1 and AFF4 act as a scaffold to assemble the Super Elongation Complex (SEC) that strongly activates transcriptional elongation of HIV-1 and cellular genes. Although they can dimerize, it is unclear whether the dimers exist and function within a SEC in vivo. Furthermore, it i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Huasong, Li, Zichong, Zhang, Wei, Schulze-Gahmen, Ursula, Xue, Yuhua, Zhou, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499153/ https://www.ncbi.nlm.nih.gov/pubmed/26007649 http://dx.doi.org/10.1093/nar/gkv541

Ejemplares similares

Schizosaccharomyces pombe Pol II transcription elongation factor ELL functions as part of a rudimentary super elongation complex
por: Gopalan, Sneha, et al.
Publicado: (2018)

AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter
por: Schulze-Gahmen, Ursula, et al.
Publicado: (2014)

Super resolution microscopy reveals how elongating RNA polymerase II and nascent RNA interact with nucleosome clutches
por: Castells-Garcia, Alvaro, et al.
Publicado: (2021)

TFIIH is an elongation factor of RNA polymerase I
por: Assfalg, Robin, et al.
Publicado: (2012)

Methylation of human eukaryotic elongation factor alpha (eEF1A) by a member of a novel protein lysine methyltransferase family modulates mRNA translation
por: Jakobsson, Magnus E., et al.
Publicado: (2017)

Directional transition from initiation to elongation in bacterial translation
por: Goyal, Akanksha, et al.
Publicado: (2015)

TEFM is a potent stimulator of mitochondrial transcription elongation in vitro
por: Posse, Viktor, et al.
Publicado: (2015)

Elongation factor TFIIS is essential for heat stress adaptation in plants
por: Szádeczky-Kardoss, István, et al.
Publicado: (2022)

Tagetitoxin inhibits transcription by stabilizing pre-translocated state of the elongation complex
por: Yuzenkova, Yulia, et al.
Publicado: (2013)

The ribosome assembly gene network is controlled by the feedback regulation of transcription elongation
por: Gómez-Herreros, Fernando, et al.
Publicado: (2017)

Ikaros interacts with P-TEFb and cooperates with GATA-1 to enhance transcription elongation
por: Bottardi, Stefania, et al.
Publicado: (2011)

The elongation factor Spn1 is a multi-functional chromatin binding protein
por: Li, Sha, et al.
Publicado: (2018)

Different elongation factors distinctly modulate RNA polymerase II transcription in Arabidopsis
por: Obermeyer, Simon, et al.
Publicado: (2023)

Transcription initiation factor DksA has diverse effects on RNA chain elongation
por: Furman, Ran, et al.
Publicado: (2012)

Control of transcription elongation by GreA determines rate of gene expression in Streptococcus pneumoniae
por: Yuzenkova, Yulia, et al.
Publicado: (2014)

The elongation factor Spt4/5 regulates RNA polymerase II transcription through the nucleosome
por: Crickard, John B., et al.
Publicado: (2017)

The mRNA degradation factor Xrn1 regulates transcription elongation in parallel to Ccr4
por: Begley, Victoria, et al.
Publicado: (2019)

Native elongation transcript sequencing reveals temperature dependent dynamics of nascent RNAPII transcription in Arabidopsis
por: Kindgren, Peter, et al.
Publicado: (2020)

The splice variants of UBF differentially regulate RNA polymerase I transcription elongation in response to ERK phosphorylation
por: Stefanovsky, Victor Y., et al.
Publicado: (2008)

The distribution of active RNA polymerase II along the transcribed region is gene-specific and controlled by elongation factors
por: Rodríguez-Gil, Alfonso, et al.
Publicado: (2010)

The transcript elongation factor SPT4/SPT5 is involved in auxin-related gene expression in Arabidopsis
por: Dürr, Julius, et al.
Publicado: (2014)

The conserved elongation factor Spn1 is required for normal transcription, histone modifications, and splicing in Saccharomyces cerevisiae
por: Reim, Natalia I, et al.
Publicado: (2020)

CDK12 globally stimulates RNA polymerase II transcription elongation and carboxyl-terminal domain phosphorylation
por: Tellier, Michael, et al.
Publicado: (2020)

A functional connection between translation elongation and protein folding at the ribosome exit tunnel in Saccharomyces cerevisiae
por: Rodríguez-Galán, Olga, et al.
Publicado: (2020)

The Serotonin Transporter Is an Exclusive Client of the Coat Protein Complex II (COPII) Component SEC24C
por: Sucic, Sonja, et al.
Publicado: (2011)

Yeast arginine methyltransferase Hmt1p regulates transcription elongation and termination by methylating Npl3p
por: Wong, Chi-Ming, et al.
Publicado: (2010)

Characterization of a functional endothelial super-enhancer that regulates ADAMTS18 and angiogenesis
por: Mushimiyimana, Isidore, et al.
Publicado: (2021)

Progesterone receptor induces bcl-x expression through intragenic binding sites favoring RNA polymerase II elongation
por: Bertucci, Paola Y., et al.
Publicado: (2013)

The chromatin remodeling factor CHD8 interacts with elongating RNA polymerase II and controls expression of the cyclin E2 gene
por: Rodríguez-Paredes, M., et al.
Publicado: (2009)

Synergistic activation of Arg1 gene by retinoic acid and IL-4 involves chromatin remodeling for transcription initiation and elongation coupling
por: Lee, Bomi, et al.
Publicado: (2016)

A super-family of transcriptional activators regulates bacteriophage packaging and lysis in Gram-positive bacteria
por: Quiles-Puchalt, Nuria, et al.
Publicado: (2013)

Inducible super-enhancers are organized based on canonical signal-specific transcription factor binding elements
por: Bojcsuk, Dóra, et al.
Publicado: (2017)

BAF155 methylation drives metastasis by hijacking super-enhancers and subverting anti-tumor immunity
por: Kim, Eui-Jun, et al.
Publicado: (2021)

A feed forward circuit comprising Spt6, Ctk1 and PAF regulates Pol II CTD phosphorylation and transcription elongation
por: Dronamraju, Raghuvar, et al.
Publicado: (2014)

A capping-independent function of MePCE in stabilizing 7SK snRNA and facilitating the assembly of 7SK snRNP
por: Xue, Yuhua, et al.
Publicado: (2010)

A complex between DYRK1A and DCAF7 phosphorylates the C-terminal domain of RNA polymerase II to promote myogenesis
por: Yu, Dan, et al.
Publicado: (2019)

H3K4 demethylase KDM5B regulates global dynamics of transcription elongation and alternative splicing in embryonic stem cells
por: He, Runsheng, et al.
Publicado: (2017)

Super-enhancer mediated regulation of adult β-globin gene expression: the role of eRNA and Integrator
por: Gurumurthy, Aishwarya, et al.
Publicado: (2021)

8-oxodG accumulation within super-enhancers marks fragile CTCF-mediated chromatin loops
por: Scala, Giovanni, et al.
Publicado: (2022)

LINE1 family member is negative regulator of HLA-G expression
por: Ikeno, Masashi, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_09vfn0bvrkpm7gp9d9n4ennvri